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ACTOS, lik oth thiazolidindions, can caus dos-latd luid tntion whn usd alon in combination with oth antidiabtic mdications and is most common whn ACTOS is usd in combination with insulin. luid tntion may lad txacbat congstiv hat ailu. Patints should b obsvd signs and symptoms congstiv hat ailu. I congstiv hat ailu dvlops, it should b managd accoding tcunt standads ca and discontinuation dos duction ACTOS must b considd [s BOX WANING , CONTAINDICATIONS , and ADVS ACTIONS ].
ACTOS can caus you body tkp xta luid (luid tntion), which lads tswlling (dma) and wight gain. xta body luid can mak som hat poblms wos lad that ailu. Hat ailu mans you hat dos not pump blood wll nough Dnot tak ACTOS i you hav sv hat ailu I you hav hat ailu with symptoms (such as shotnss bath swlling), vn i ths symptoms a not sv, ACTOS may not b ight you.
Liv tsts (sum alanin and aspatat aminotansass, alkalin phosphatas, and total biliubin) should b obtaind pitinitiating ACTOS. outin piodic monitoing liv tsts duing tatmnt with ACTOS is not commndd in patints without liv disas. Patints whhav liv tst abnomalitis pitinitiation ACTOS wha ound thav abnomal liv tsts whil taking ACTOS should b managd as dscibd und Wanings and Pcautions [s WANINGS AND PCAUTIONS and CLINICAL PHAMACOLOGY ].
Initiation in patints with stablishd NYHA Class III IV hat ailu [s BOX WANING ]. Us in patints with known hypsnsitivity tpioglitazon any oth componnt ACTOS.
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