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Information about Methotrexate.
This medicine can pass into body fluidsurinefecesvomitCaregivers should wear rubber gloves while cleaning up a patient’s body fluidshandling contaminated trash or laundry or changing diapersWash hands before and after removing glovesWash soiled clothing and linens separately from other laundry.
Do not take these drugs with methotrexateWhen used with methotrexatethese drugs can cause dangerous effects in your bodyExamples of these drugs include:
When this medication is used with radiation treatmentit may rarely increase the risk of tissue and bone damageDiscuss the risks and benefits of your treatment with your doctor.
Live vaccinesWhen used with methotrexatelive vaccines raise your risk of infectionThe vaccine may also not work as wellLive vaccinessuch as FluMistare vaccines that contain small amounts of livebut weakenedviruses
When this medication is used with radiation treatmentit may rarely increase the risk of tissue and bone damageDiscuss the risks and benefits of your treatment with your doctor.
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in postmarketing experience, overdose with methotrexate has generally occurred with oral and intrathecal administration, although intravenous and intramuscular overdose have also been reported.