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Administration of isotretinoin should be avoided shortly beforeduringand shortly after minocycline therapyEach drug alone has been associated with pseudotumor cerebriSee PRECAUTIONS
Upper respiratory tract infections caused by Streptococcus pneumoniaeSkin and skin structure infections caused by Staphylococcus aureusNoteMinocycline is not the drug of choice in the treatment of any type of staphylococcal infection
Intracranial hypertensionpseudotumor cerebrihas been associated with use of tetracyclines including minocyclineavoid concomitant use of isotretinoin and minocyclineisotretinoin is also known to cause pseudotumor cerebrialthough intracranial hypertension typically resolves after discontinuation of treatmentrisk of permanent visual loss existsseek ophthalmologic evaluation if visual disturbance occurs during treatmentsince intracranial pressure can remain elevated for weeks after drug cessationmonitor until patient stabilizes.
Read the Patient Information Leaflet if available from your pharmacist before you start taking minocycline and each time you get a refillIf you have any questionsask your doctor or pharmacist.
Renal toxicityInterstitial nephritisElevations in BUN have been reported and are apparently dose relatedSee WARNINGSReversible acute renal failure has been reported.
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