In any regard, the the acute administration of minocycline failed to ameliorate depression in the olfactory bulbectomy model, but it appeared to significantly inhibit mechanical allodynia in ob and sham rats.
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Intracranial hypertensionpseudotumor cerebrihas been associated with use of tetracyclines including minocyclineavoid concomitant use of isotretinoin and minocyclineisotretinoin is also known to cause pseudotumor cerebrialthough intracranial hypertension typically resolves after discontinuation of treatmentrisk of permanent visual loss existsseek ophthalmologic evaluation if visual disturbance occurs during treatmentsince intracranial pressure can remain elevated for weeks after drug cessationmonitor until patient stabilizes.
Minocycline passes into breast milk and may affect bone and tooth development in a nursing babyYou should not breast-feed while you are taking minocycline.
For 2 hours before or after you take minocyclineAvoid taking antacidslaxativesmultivitaminsor supplements that contain calciummagnesiumor ironThese other medicines can make it harder for your body to absorb minocycline.
Do not crushchewor break an extended-release capsule or tabletSwallow it whole.
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in adults with periodontitis, a modified-release subgin-gival gel containing minocycline hydrochloride has been inserted into the periodontal pocket as an adjunct to scaling and root planing; each cartridge contains the equivalent of 1 mg of minocycline minocin 50mg, 100mg and the total used depends on the size, shape, and number of pockets being treated.