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Pancreatitishepatotoxicityand peripheral neuropathy have occurred when hydroxyurea was administered concomitantly with antiretroviral drugsincluding didanosine and stavudinesee DRUG INTERACTIONS
Read the Medication Guide if available from your pharmacist before you start taking hydroxyurea and each time you get a refillIf you have any questionsask your doctor or pharmacist.
Hydroxyurea distributes throughout the body with a volume of distribution approximating total body water.
As hydroxyurea is mainly eliminated from the body via the kidneysdose reductions may be necessary in patients with reduced kidney function.
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