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Data from a XENICAL and cyclosporine drug interaction study indicate a reduction in cyclosporine plasma levels when XENICAL was coadministered with cyclosporineThereforeXENICAL and cyclosporine should not be simultaneously coadministeredTo reduce the chance of a drug-drug interactioncyclosporine should be taken at least 3 hours before or after XENICAL in patients taking both drugsIn additionin those patients whose cyclosporine levels are being measuredmore frequent monitoring should be considered.
Loose stoolsor an urgent need to go to the bathroominability to control bowel movements;
Dietary fats need to be broken down into smaller pieces before the body can absorb themOrlistat works by blocking the enzyme that breaks down fats in your dietThis undigested fat then passes out of your body in your bowel movementOrlistat does not block the absorption of calories from sugar and other non-fat foodsso you still need to restrict your total intake of calories.
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