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DRSP is a spironolactone analogue which has anti-mineralocorticoid propertiesSerum concentration of potassium and sodiumand evidence of metabolic acidosisshould be monitored in cases of overdose.
Some studies suggest that COCs are associated with an increase in the risk of cervical cancer or intraepithelial neoplasiaHoweverthere is controversy about the extent to which these findings may be due to differences in sexual behavior and other factors.
COCs containing EE may inhibit the metabolism of other compoundsCOCs have been shown to significantly decrease plasma concentrations of lamotriginelikely due to induction of lamotrigine glucuronidationThis may reduce seizure controlthereforedosage adjustments of lamotrigine may be necessaryConsult the labeling of the concurrently-used drug to obtain further information about interactions with COCs or the potential for enzyme alterations.
It is important to note that taking Yasmin increases your risk of developing blood clotsand having a strokeor heart attack.
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prior to the initiation or reinstitution of yasmin a complete medical history including family history should be taken and pregnancy must be ruled out.